The research goal of the Metabolic Research Unit is to understand how metabolism is regulated and what role hormones play for maintaining normal fat and muscle mass. Special focus is on establishing hormonal interactions in the regulation of metabolism, and the use of resistance training and diabetes drugs to suppress cancer progression. Located at the Blacktown Clinical School and Research Centre, Blacktown Hospital, the Metabolic Research Unit is equipped to perform a wide range of body composition, energy expenditure, substrate utilization, physical capacity, muscle strength, and balance assessments. State-of-the-art techniques are implemented using stable isotopes to investigate whole body protein metabolism, urea turnover, and liver VLDL production. This laboratory is the only one in Australia who can perform such complex stable isotope studies in humans. The focus is to establish a network of collaborative projects in WSLHD in endocrine, metabolic and cancer research, investigating hormonal control of metabolism and cancer development, integrating endocrinology and oncology at WSLHD.